Biosimulators
Bio Simulators are substances that help improve skin quality, renew collagen and reduce signs of aging. aesthafill, based on polylactic acid, stimulates collagen production in the skin and provides long-term results. The treatment is performed by injection into specific areas such as the face and neck, and provides a natural result without surgery, with minimal risk. Suitable for those interested in improving the appearance of youthful and healthy skin.
Improving skin texture with biostimulants:
Improving the appearance of facial skin and renewing collagen
AESTHEFill and Karizma are innovative biosimulators designed to improve the appearance of facial skin by renewing collagen and reducing signs of aging. aesthafill is based on polylactic acid and gradually stimulates collagen production, while maintaining a natural appearance and durability over time. Karizma, pure human collagen, works to renew the extracellular matrix and increase skin elasticity. Both treatments are performed by non-invasive injection and provide a natural result in a short time, with minimal risk and quick recovery.
Who Is Aesthafill and Karizma Treatment Suitable For?
- Want to improve skin elasticity and reduce the appearance of fine lines and wrinkles
- Seek a non-invasive option to restore facial volume and rejuvenate skin tone
- Show visible signs of aging such as eye hollows, sagging cheeks, or volume loss in the chin
- Desire immediate, natural-looking results with continued improvement over time
- Prefer long-lasting outcomes without the need for surgery
- Value personalized, professional care tailored to their unique skin needs
The Treatment Process
How is Aesthafill and Karizma Treatment Performed by Dr. Chen Shevel?
How is Aesthafill and Karizma Treatment Performed by Dr. Chen Shevel?
AESTHEFill – an innovative biosimulator
Aesthafill is a biosimulator made from polylactic acid, which helps thicken and firm the skin. It gradually stimulates natural collagen production, which leads to improved skin appearance and reduced pigmentation. The combination of uniform dispersion of the material allows for personalized treatment for each patient, while maintaining high safety and effectiveness. The treatment is performed by cannula in most parts of the face (except the forehead and nose) and in the neck area.
Who Is It For?
Benefits of Aesthafill Treatment
Charisma
Who Is It For?
- Those looking to improve skin elasticity and reduce visible signs of aging
- Individuals who need skin thickening and texture enhancement, especially in collagen-depleted areas
- Anyone seeking a long-lasting solution with gradual, stable, and natural results
- Patients preferring a non-invasive treatment over surgery, with natural and resilient outcomes
The Benefits of Karisma Treatment
Boosts natural collagen synthesis and reduces visible signs of aging
Provides deep hydration and enhances skin elasticity
Delivers immediate texture improvement with natural, long-lasting results
Reduces pigmentation and improves overall skin appearance
Karisma RH Collagen Contains:
1. Rh Collagen α1 Polypeptide Chain:
Stimulates Type I collagen peptide synthesis in human dermal fibroblasts.
The α1 chain promotes and facilitates the coiling of procollagen triple helix chains.
2. High Molecular Weight Hyaluronic Acid (HMW-HA / 400 mg):
- Deep hydration and maintenance of a favorable environment
for fibroblast growth and metabolism - Antioxidant activity and improved skin elasticity
3. Carboxymethylcellulose (CMC):
- Inhibits the hyaluronidase enzyme
- Preserves endogenous hyaluronic acid
- Slows the activity of matrix metalloproteinases (MMP)
Karisma Collagen is a bio-regenerative dermal filler based on pure injectable collagen.
In the pursuit of youthful, glowing skin, Karisma stands out as a leader among collagen-inducing fillers.
Its innovative formula and proven effectiveness make it a breakthrough in restoring the skin’s natural collagen production.
Salmon DNA Injections (PN / PDRN Therapy)
Advanced Skin Regeneration & Repair
What Are Salmon DNA Injections?
Salmon DNA injections, also known as PN (Polynucleotides) or PDRN therapy, are an advanced biostimulatory skin treatment derived from purified DNA fragments extracted from salmon. These polynucleotides are highly biocompatible with human skin and are widely used in aesthetic and regenerative medicine to repair, regenerate, and improve skin quality from within.
Unlike traditional fillers that add volume, salmon DNA injections work at a cellular level, stimulating natural healing processes and improving the skin’s structure and function over time.
How Do Salmon DNA Injections Work?
Polynucleotides act as powerful biological stimulators that encourage cellular regeneration, improve microcirculation, support collagen and elastin production, enhance skin hydration and elasticity, and reduce inflammation and oxidative stress.
What Areas Can Be Treated?
Face, under-eye area, neck, décolletage, hands, acne scars, and sun-damaged skin.
Who Is This Treatment Suitable For?
Suitable for women and men experiencing early signs of aging, dull or dehydrated skin, fine lines, or loss of elasticity, and for those seeking skin rejuvenation without added volume.
Treatment Process
Results
Safety & Medical Oversight
Frequently Asked Questions (FAQ)
What is Aesthafill and how does it work?
What is Karizma and how does it work?
What is the difference between Aesthafill and Karizma?
How long does the treatment take?
How long do the results last?
Karizma: Offers immediate results with ongoing improvement; maintenance treatments help prolong results